Transferases
A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into subclasses, based on the functional groups the enzymes transfer and the substrate specificity.
[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2175 | 3PO | Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. | €65.00 | |
| 1902 | 4μ8C | IRE1α inhibitor | €105.00 | |
| 1909 | A 1070722 | Selective inhibitor of GSK-3 | €95.00 | |
| 1831 | A 66 | PI3K inhibitor (p110-α specific) | €95.00 | |
| 1466 | A 769662 | AMPK activator | €85.00 | |
| 1698 | A 770041 | Orally active src-family selective lck inhibitor | €135.00 | |
| 2059 | A 922500 | Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor | €105.00 | |
| 2705 | A-196 | Potent and selective inhibitor of SUV4-20 | €105.00 | |
| 2720 | A-92 | Inhibitor of GCN2 (EIF2AK4) | €145.00 | |
| 2880 | ABC294640 | Selective and orally available SphK2 (or SK2) inhibitor | €125.00 | |
| 2289 | ABT 702 | The first, non-nucleoside adenosine kinase (ADK) inhibitor | €120.00 | |
| 1593 | ABT 888 | PARP inhibitor | €55.00 | |
| 2888 | ABT 888 dihydrochloride | PARP inhibitor | €95.00 | |
| 2857 | Acalisib | PI3K inhibitor (p110 δ specific) | €120.00 | |
| 1291 | AEG 3482 | JNK inhibitor | €85.00 | |
Categories
- Filter by Endogenous Substrate
- Ack1-AR-ATM signaling (3)
- ADP (1)
- Amyloids (1)
- AP2 (1)
- ATP (1)
- B-Cell Transformation (7)
- BCAA (1)
- C-Nap1,PP1,Nek2 (1)
- Cation-Cl− cotransporters (CCCs) (1)
- CDK1 (1)
- Ceramide (1)
- Cholesterol (1)
- Cyclin Dependent (CDK) (11)
- Cytoskeleton (1)
- Deoxyuridine monophosphate (dUMP) (1)
- Diacylglycerol (1)
- DNA (1)
- DNA-damage response (4)
- DNA-RNA (54)
- Farnesyl substrates (CaaX motif) (1)
- Fructose 6-phosphate (2)
- Geranyl Diphosphate (1)
- Glucose (4)
- Glucose Homeostasis (4)
- Glutathion (GSH) (1)
- Glycogen (1)
- HGF (1)
- Histone (23)
- IκB (7)
- JAK-STAT Pathway (15)
- Kynurenine, L- (2)
- LCCs, RyRs, and PLB (2)
- MAPK (42)
- MEK (11)
- Nicotinamide D-ribonucleotide (4)
- Non Selective (11)
- Non Selective (ADF-cofilin) (4)
- Non Selective (Arginine Sites Proteins) (8)
- Non Selective (CHK2; p53) (8)
- Non Selective (Glucocorticoid) (1)
- Non Selective (Histone; Survivin; Topo) (3)
- Non Selective (Histone; Survivin; Topo; TPX2) (5)
- Non Selective (Histone; Survivin; Topo; TPX2); JAK-STAT Pathway; Non Selective (Phosphorylation Substrates) (1)
- Non Selective (LIM; p53; TPX2) (4)
- Non Selective (Lysine Sites Proteins) (1)
- Non Selective (Mitotic Spindle Checkpoint) (4)
- Non Selective (Phosphorylation Substrates) (74)
- Non Selective (Phosphorylation Substrates); MAPK (1)
- Non Selective (Phosphorylation Substrates); MAPK; FGF-VEGF (1)
- Non Selective (Ribosomal proteins) (5)
- Non Selective (Tyrosine Specific Phosphomonoesters) (1)
- Non Selective (Ubiquitin peptides) (1)
- Palmitoyl-CoA; L-serine (1)
- PDGF-FGF-VEGF (1)
- Phosphatidylinositol (65)
- Pyruvate (2)
- SCF-VEGF (1)
- Serotonin (1)
- Sonic Hedgehog (2)
- Sphingosine (5)
- Sphingosine-1-phosphate (1)
- T-Cell signaling (1)
- TGF-β (1)
- Thymidylate pathway (1)
- Unfolded Protein Response (EIF2 Selective) (3)
- Wnt proteins (3)
- Filter by Action