Transferases

A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into  subclasses, based on the functional groups the enzymes transfer and the substrate specificity.


[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.

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Axon ID Name Description From price
2786 (±)-PH 797804 Inhibitor of p38α MAPK €115.00
2537 1,5-Isoquinolinediol PARP1 inhibitor and neuroprotective agent €50.00
1892 1-NM-PP1 Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) €95.00
1496 3-Aminobenzamide Competitive small molecule inhibitor of PARP €40.00
2175 3PO Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. €65.00
1902 4μ8C IRE1α inhibitor €105.00
3476 5-NIdR Potent inhibitor of translesion DNA synthesis (TLS) €120.00
1909 A 1070722 Selective inhibitor of GSK-3 €95.00
1831 A 66 PI3K inhibitor (p110-α specific) €95.00
1466 A 769662 AMPK activator €85.00
1698 A 770041 Orally active src-family selective lck inhibitor €140.00
2059 A 922500 Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor €105.00
2705 A-196 Potent and selective inhibitor of SUV4-20 €105.00
2720 A-92 Inhibitor of GCN2 (EIF2AK4) €145.00
2880 ABC294640 Selective and orally available SphK2 (or SK2) inhibitor €125.00
2289 ABT 702 The first, non-nucleoside adenosine kinase (ADK) inhibitor €120.00
1593 ABT 888 PARP inhibitor €40.00
2888 ABT 888 dihydrochloride PARP inhibitor €95.00
2857 Acalisib PI3K inhibitor (p110 δ specific) €120.00
3384 Acyclovir Highly selective inhibitor of herpes virus DNA polymerase €60.00
1291 AEG 3482 JNK inhibitor €85.00
1529 AG 014699 PARP1 inhibitor €60.00
1378 AG 490 JAK2 inhibitor €65.00
3515 AG-270 First-in-class, highly potent, selective, orally bioavailable MAT2A inhibitor €180.00
2389 AICAR Potent AMPK activator and inducer of differentiation of NSCs €45.00
2031 AIM 100 Specific inhibitor of Ack1 tyrosine kinase (also known as TNK2) €95.00
3408 AKI603 Inhibitor of Aurora A kinase €145.00
2540 Akt Inhibitor VIII Inhibitor of Akt1 and 2 with significant off-side effects (CaMKIα and AhR) €95.00
2925 Alpelisib PI3K inhibitor (p110-α specific) €90.00
2971 Amcasertib First-in-class stemness kinase inhibitor €145.00

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