Transferases
A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into subclasses, based on the functional groups the enzymes transfer and the substrate specificity.
[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2175 | 3PO | Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. | €65.00 | |
| 1902 | 4μ8C | IRE1α inhibitor | €105.00 | |
| 1909 | A 1070722 | Selective inhibitor of GSK-3 | €95.00 | |
| 1831 | A 66 | PI3K inhibitor (p110-α specific) | €95.00 | |
| 1466 | A 769662 | AMPK activator | €85.00 | |
| 1698 | A 770041 | Orally active src-family selective lck inhibitor | €135.00 | |
| 2059 | A 922500 | Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor | €105.00 | |
| 2705 | A-196 | Potent and selective inhibitor of SUV4-20 | €105.00 | |
| 2720 | A-92 | Inhibitor of GCN2 (EIF2AK4) | €145.00 | |
| 2880 | ABC294640 | Selective and orally available SphK2 (or SK2) inhibitor | €125.00 | |
| 2289 | ABT 702 | The first, non-nucleoside adenosine kinase (ADK) inhibitor | €120.00 | |
| 1593 | ABT 888 | PARP inhibitor | €55.00 | |
| 2888 | ABT 888 dihydrochloride | PARP inhibitor | €95.00 | |
| 2857 | Acalisib | PI3K inhibitor (p110 δ specific) | €120.00 | |
| 1291 | AEG 3482 | JNK inhibitor | €85.00 | |
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