HIV
The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans. HIV infects and destroys CD4 T cells, neutralizing antibodies have little effect on virus replication, and cytotoxic T lymphoctes (CTLs) limit HIV replication without stopping it. Over time, HIV infection causes acquired immunodeficiency syndrome (AIDS)[1,2]. The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs. Current antiviral treatments can reduce HIV-associated morbidity, prolong survival, and prevent HIV transmission. Combination antiretroviral therapy (cART) containing preferably three active drugs from two or more classes is required for durable virologic suppression[3].
Axon ID | Name | Description | From price | |
---|---|---|---|---|
2855 | Dolutegravir | HIV integrase inhibitor | €135.00 | |
3120 | Raltegravir | Potent, selective and orally bioavailable HIV integrase inhibitor | €90.00 |