Bulk Inquiry
NSC 625987
- Soluble in DMSO
- MF: C15H13NO2S
- MW: 271.33
Description
NSC 625987 is a selective and potent cyclin-dependent kinase 4 (CDK4) inhibitor.
CDK4 drives phosphorylation of retinoblastoma protein and progression through the G1/S cell-cycle checkpoint. NSC 625987 is useful for investigating CDK4-dependent proliferation, cell-cycle arrest and cancer-related signaling.
Key Features
- Selective CDK4 inhibitor
- Targets cyclin D-CDK4 cell-cycle signaling
- Useful for studying G1/S checkpoint control
- Relevant to antiproliferative and cancer pathway research
Applications
- CDK4 kinase assays
- Cell-cycle arrest studies
- RB phosphorylation analysis
- Cancer cell proliferation research
More Information
| Parent CAS No. | 141992-47-4 |
|---|---|
| Chemical Name | 1,4-Dimethoxy-10H-acridine-9-thione |
| SMILES | C12C(=S)C3C=CC=CC=3NC=1C(OC)=CC=C2OC |
| MFCD | MFCD08276925 |
| InChi | InChI=1S/C15H13NO2S/c1-17-11-7-8-12(18-2)14-13(11)15(19)9-5-3-4-6-10(9)16-14/h3-8H,1-2H3,(H,16,19) |
| InChiKey | KFAKESMKRPNZTM-UHFFFAOYSA-N |
| CID | 3004085 |
| Short Description | CDK4 inhibitor |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1505 | PD0332991 hydrochloride |
From $88.00 |
| 1530 | RO 3306 |
From $88.00 |
| 1539 | AT 7519 mesylate |
From $88.00 |
| 1614 | SNS 032 |
From $93.50 |
| 1776 | Dinaciclib |
From $99.00 |
| 1966 | AZD5438 |
From $88.00 |
| 1983 | R 547 |
From $104.50 |
| 2052 | Palbociclib isethionate |
From $137.50 |
| 2268 | XL 413 hydrochloride |
From $132.00 |
| 2273 | LEE 011 |
From $77.00 |
| 2695 | NSC 23005 sodium |
From $99.00 |
| 3184 | SR-4835 |
From $143.00 |
| 3228 | CDK inhibitor CR8 |
From $143.00 |
| 3402 | THZ531 |
From $143.00 |
| 3525 | ETP-47799 |
From $99.00 |
| 3535 | XY028-140 |
From $132.00 |
| 3693 | PF-06873600 |
From Inquiry |
| 3753 | PF-07104091 |
From $154.00 |
| 3762 | PF-07220060 |
From $143.00 |
| 3876 | OTS-964 |
From Inquiry |
| 4071 | AMG-925 |
From Inquiry |
| 4097 | OTS964 hydrochloride |
From $132.00 |
| 4265 | AZD8421 |
From Inquiry |
