AZD8421
- Optical Purity: 98% e.e.
- Soluble in DMSO
- MF: C18H32N8O3S
- MW: 440.57
Description
AZD8421 is an orally bioavailable selective inhibitor of CDK2 (IC50 = 9 nM), highly selective over other CDK inhibitors such as CDK1, CDK4, CDK6 and CDK9.
More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | (S)-N-Ethyl-3-(9-ethyl-2-((2R,3S)-2-hydroxypentan-3-ylamino)-9H-purin-6-ylamino)pyrrolidine-1-sulfonamide |
| extra_info | Sold in collaboration with Chemietek |
| SMILES | C1(N[C@H]2CCN(S(NCC)(=O)=O)C2)N=C(N[C@H]([C@H](O)C)CC)N=C2N(CC)C=NC=12 |&1:2,16,17,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | CDK2 inhibitor |
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