Bulk Inquiry
ETP-47799
- CDK8/19i
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C14H15N5
- MW: 253.3
Description
ETP-47799 is a potent CDK8/19 inhibitor with IC50 values of 2.9 nM and 14.1 nM for CDK8 and CDK19, respectively. ETP-47799 stimulates Mediator recruitment of RNA Pol II. This effectively hyper-activates enhancers and stabilizes the transcriptional program of naïve pluripotent cell identity.
More Information
| Parent CAS No. | 923596-52-5 |
|---|---|
| Chemical Name | N-Propyl-3-(pyridin-4-yl)imidazo[1,2-b]pyridazin-6-amine |
| MFCD | N.A. |
| Short Description | CDK8/CDK19 inhibitor |
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