Transferases

A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into  subclasses, based on the functional groups the enzymes transfer and the substrate specificity.


[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.

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Axon ID Name Description From price
2863 AMI-1 Inhibitor of PRMT €99.00
1490 Anacardic acid A HAT inhibitor €60.00
3008 AOH1160 First-in-class, potent and orally available PCNA inhibitor €120.00
3328 APIO-EE-07 Dual RSK1/MSK2 inhibitor €140.00
2611 APS-2-79 Inhibitor of KSR and oncogenic Ras signaling €90.00
2167 AR-A 014418 ATP-competitive GSK-3 inhibitor €85.00
3041 ARN 3236 Potent, selective, ATP-competitive, and orally available inhibitor of SIK2 €95.00
2187 AS 1892802 Potent, selective, ATP-competitive ROCK inhibitor €95.00
1424 AS 252424 PI3K inhibitor (p110-γ specific) €85.00
1436 AS 252424 bispotassium salt PI3K inhibitor (p110-γ specific) €95.00
2002 AS 602801 JNK inhibitor, which inhibited JNK1, JNK2 and JNK3 €70.00
2179 ASK1 Inhibitor 10 Potent, selective, and orally bioavailable ASK1 inhibitor €125.00
2005 ASP 3026 Inhibitor of the oncogenic fusion kinase EML4-ALK €80.00
2166 AT 13148 dihydrochloride ATP-competitive inhibitor of multi-AGC kinases €70.00
1539 AT 7519 mesylate CDK inhibitor €80.00

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