Hydrolases

The group of hydrolases (EC 3.-.-.-) consists of 13 subgroups, as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. Only few of them are represented in the Axon Ligands™ catalogue. The enzymes that catalyze the hydrolysis of various bonds are classified by the nature of the chemical bonds they cleave. Examples of enzymes of this group of enzymes are esterases, peptidases, and deacetylases.

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Axon ID Name Description From price
1666 A 357300 hydrochloride MetAP2 inhibitor €95.00
3000 ABX-1431 Highly potent, selective, brain-penetrant, and orally available MAGL inhibitor  Recently added €135.00
2083 ADAMTS-5 inhibitor Selective inhibitor of ADAMTS-5 (aggrecanase-2) €135.00
1571 AG 7088 HRV3C protease inhibitor €95.00
2269 AK 1 Potent inhibitor of SIRT with good selectivity for SIRT2 over SIRT1 and SIRT3 €90.00
2270 AK 7 Potent, brain-permeable and selective inhibitor of SIRT2 €90.00
2137 APE1 Inhibitor III Inhibitor of apurinic/apyrimidinic endonuclease 1 (APE1) €105.00
1754 Apixaban Factor Xa inhibitor €125.00
2006 Apoptosis Activator 2 A cell-permeable apoptosis activator €75.00
2251 Apoptozole Inhibitor of ATPase activity of Hsc70 and Hsp70 €95.00
1957 Apremilast PDE4 inhibitor €105.00
2394 AR-42 HDAC inhibitor €125.00
2136 AR03 Inhibitor of apurinic/apyrimidinic endonuclease 1 (APE1) €105.00
2307 ARM1 hydrobromide Novel type of LTA4H inhibitor that selectively blocks the conversion of LTA4 into LTB4 €92.00
2941 ARN 272 Selective inhibitor of FAAH-like anandamide transporter (FLAT) €90.00

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