Hydrolases

The group of hydrolases (EC 3.-.-.-) consists of 13 subgroups, as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. Only few of them are represented in the Axon Ligands™ catalogue. The enzymes that catalyze the hydrolysis of various bonds are classified by the nature of the chemical bonds they cleave. Examples of enzymes of this group of enzymes are esterases, peptidases, and deacetylases.

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Axon ID Name Description From price
1666 A 357300 hydrochloride MetAP2 inhibitor €95.00
2083 ADAMTS-5 inhibitor Selective inhibitor of ADAMTS-5 (aggrecanase-2) €135.00
1571 AG 7088 HRV3C protease inhibitor €135.00
2269 AK 1 Potent inhibitor of SIRT with good selectivity for SIRT2 over SIRT1 and SIRT3 €90.00
2270 AK 7 Potent, brain-permeable and selective inhibitor of SIRT2 €90.00
1754 Apixaban Factor Xa inhibitor €125.00
2006 Apoptosis Activator 2 A cell-permeable apoptosis activator €75.00
2251 Apoptozole Inhibitor of ATPase activity of Hsc70 and Hsp70 €95.00
1957 Apremilast PDE4 inhibitor €105.00
2307 ARM1 hydrobromide Novel type of LTA4H inhibitor that selectively blocks the conversion of LTA4 into LTB4 €92.00
2578 ASB14780 Potent, orally available inhibitor of cPLA2α; antiinflammatory drug €120.00
2276 Atglistatin Potent and selective inhibitor of adipose triglyceride lipase (ATGL) €90.00
2661 AZD2716 Potent secreted phospholipase A2 (sPLA2) inhibitor  Recently added €145.00
1125 BACE-1 Inhibitor BACE 1 inhibitor €110.00
2154 Balicatib Selective inhibitor of cathepsin K €80.00

Items 1 to 15 of 177 total

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