Amidases are ubiquitous enzymes and biological functions of these enzymes vary widely. Their proteins structures revealed that aliphatic amidases share the typical a/b hydrolase fold (like nitrilase superfamily) and signature amidases are evolutionary related to aspartic proteinases. They hydrolyze a wide variety of amides (short chain aliphatic amides, mid-chain amides, arylamides, α-aminoamides and α-hydroxyamides) and can be grouped on the basis of their catalytic site and preferred substrate.
 Amidases: versatile enzymes in nature. M. Sharma, N.N. Sharma, T.C. Bhalla. Rev. Environ. Sci. Biotechnol. 2009, 8, 343-366.
|Axon ID||Name||Description||From price|
|2000||CHIR 090||Potent and selective LpxC inhibitor||€145.00|
|1939||LpxC inhibitor 1a||Potent antibacterial LpxC inhibitor (gram-negative infections)||€135.00|
|2113||PF 05081090||LpxC inhibitor for treatment of gram-negative infections||€95.00|
|1711||PF 3845||Selective fatty acid amide hydrolase (FAAH) inhibitor||€115.00|
|2041||Sulbactam sodium||An irreversible inhibitor of β-lactamase||€70.00|