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ARN 272
Axon 2941
CAS:
488793-85-7
Purity:
98%
- Soluble in DMSO
- MF: C27H20N4O2
- MW: 432.47
Description
ARN 272 is a selective competitive antagonist of the interaction of anandamide with FAAH-like anandamide transporter (IC50 value of 1.8 µM). Moreover, ARN 272 prevents anandamide internalization in vitro, interrupts anandamide deactivation in vivo, and exerts profound analgesic effects in rodent models of nociceptive and inflammatory pain, which are mediated by CB1 cannabinoid receptors.
More Information
| Parent CAS No. | 488793-85-7 |
|---|---|
| Chemical Name | 4-(4-(4-Hydroxyphenyl)phthalazin-1-ylamino)-N-phenylbenzamide |
| SMILES | C1C2C(C3C=CC(O)=CC=3)=NN=C(NC3C=CC(C(=O)NC4C=CC=CC=4)=CC=3)C=2C=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C27H20N4O2/c32-22-16-12-18(13-17-22)25-23-8-4-5-9-24(23)26(31-30-25)28-21-14-10-19(11-15-21)27(33)29-20-6-2-1-3-7-20/h1-17,32H,(H,28,31)(H,29,33) |
| InChiKey | UPKNGUQNXSMHBE-UHFFFAOYSA-N |
| CID | 1386351 |
| Short Description | FLAT inhibitor |
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