Plasminogen activator inhibitor-1 (PAI-1)

Plasminogen activator inhibitor-1 (PAI-1)

Plasminogen activator inhibitor (PAI-1; EC 3.4.21.68) a serine protease inhibitor, is involved in numerous processes including thrombosis and fibrosis. Its inhibition may thus yield important cardio- and reno-protective benefits. Studies in mice overexpressing human PAI-1 also implicate its involvement in broader biological abnormalities, including alopecia, amyloidosis, and polycystic ovarian syndrome.

Read More
sort-descending
  • Tiplaxtinin
    1383
    Tiplaxtinin
    The price depends on the options chosen on the product page

    From $77.00

  • T 1776Na
    1769
    T 1776Na
    The price depends on the options chosen on the product page

    From $88.00

  • TM 5275
    2344
    TM 5275
    The price depends on the options chosen on the product page

    From $115.50

  • TM 5441
    2734
    TM 5441
    The price depends on the options chosen on the product page

    From $104.50

  • SK-216
    2838
    SK-216
    The price depends on the options chosen on the product page

    From $115.50

  • ACT001
    3590
    ACT001
    The price depends on the options chosen on the product page

    From $231.00

  • PAZ-417
    3710
    PAZ-417
    The price depends on the options chosen on the product page

    From $143.00

7 Items

More About Plasminogen activator inhibitor-1 (PAI-1)

Plasminogen activator inhibitor (PAI-1; EC 3.4.21.68) a serine protease inhibitor, is involved in numerous processes including thrombosis and fibrosis. Its inhibition may thus yield important cardio- and reno-protective benefits. Studies in mice overexpressing human PAI-1 also implicate its involvement in broader biological abnormalities, including alopecia, amyloidosis, and polycystic ovarian syndrome[1].

[1] Y. Izuhara et al. A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates. J. Cereb. Blood Flow Metab. 2010, 30, 904-912.

Loading...