Rac

Rac

Ras-related C3 botulinum toxin substrate 1 (Rac1; EC 3.6.5.2) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and a member of the Rac subfamily of the small monomeric Ras homolog (Rho) family of GTPases. Members of the Rho family, including Rho, Rac, and Cdc42, control the assembly and organization of the actin cytoskeleton in mammalian cells. They mediate diverse biological processes, including neuronal morphogenesis, tumor invasion, and bone formation, and act in a coordinated manner to modulate cellular functions.

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  • NSC 23766
    1578
    NSC 23766
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  • EHop 016
    2351
    EHop 016
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  • MBQ-167
    2777
    MBQ-167
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  • ZINC69391
    3790
    ZINC69391
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More About Rac

Ras-related C3 botulinum toxin substrate 1 (Rac1; EC 3.6.5.2) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and a member of the Rac subfamily of the small monomeric Ras homolog (Rho) family of GTPases. Members of the Rho family, including Rho, Rac, and Cdc42, control the assembly and organization of the actin cytoskeleton in mammalian cells. They mediate diverse biological processes, including neuronal morphogenesis, tumor invasion, and bone formation, and act in a coordinated manner to modulate cellular functions[1].

RAS GTPases listed: HRAS, Rab7, Rac

[1] M. Onish et al. Inhibition of Rac1 promotes BMP-2-induced osteoblastic differentiation. Cell Death Dis. 2013, 4, e698

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