Rho

Rho GTPase and its downstream effector, Rho kinase (ROCK), have been demonstrated to be involved in cell adhesion, motility, and contraction. Upregulation of the RhoA/ROCK signaling pathway causes an increase of inflammation, immune cell migration, apoptosis, coagulation, contraction, and cell adhesion in pulmonary endothelial cells[1].


[1] F Abedi et al. Acute lung injury: The therapeutic role of Rho kinase inhibitors. Pharmacol Res. 2020 May;155:104736.

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Axon ID Name Description From price
2753 CCG 232601 Rho/MRTF/SRF transcriptional pathway inhibitor €160.00
3092 CCG-203971 Rho/MRTF/SRF transcriptional pathway inhibitor €60.00
3069 CCG-222740 Potent and selective Rho/MRTF/SRF transcriptional pathway inhibitor €145.00

3 Item(s)

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