Rho

Rho

Rho GTPase and its downstream effector, Rho kinase (ROCK), have been demonstrated to be involved in cell adhesion, motility, and contraction. Upregulation of the RhoA/ROCK signaling pathway causes an increase of inflammation, immune cell migration, apoptosis, coagulation, contraction, and cell adhesion in pulmonary endothelial cells.

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  • CCG 232601
    2753
    CCG 232601
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    3069
    CCG-222740
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  • CCG-203971
    3092
    CCG-203971
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3 Items

More About Rho

Rho GTPase and its downstream effector, Rho kinase (ROCK), have been demonstrated to be involved in cell adhesion, motility, and contraction. Upregulation of the RhoA/ROCK signaling pathway causes an increase of inflammation, immune cell migration, apoptosis, coagulation, contraction, and cell adhesion in pulmonary endothelial cells[1].

[1] F Abedi et al. Acute lung injury: The therapeutic role of Rho kinase inhibitors. Pharmacol Res. 2020 May;155:104736.
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