Esterases (Thio-)

Thioesterases are enzymes that hydrolyse thioesters between a carbonyl group and a sulfur atom. in the presence of water, and are identified as members of E.C.3.1.2. Substrates of 15 of these 27 groupings contain coenzyme A (CoA), two contain acyl carrier proteins (ACPs), four have glutathione or its derivatives, one has ubiquitin, and two contain other moieties. Acetyl-CoA hydrolase, palmitoyl-CoA hydrolase, succinyl-CoA hydrolase, formyl-CoA hydrolase, acyl-CoA hydrolase are a few examples of this group of enzymes[1].


[1] DC Cantu et al. Thioesterases: a new perspective based on their primary and tertiary structures. Protein Sci. 2010 Jul;19(7):1281-95.

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3968 Darapladib Selective lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor  Recently added Inquire
2646 ML348 Selective inhibitor for acyl-protein thioesterase APT1 (aka LYPLA1) €95.00

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