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MF C25H19NO3SMW 413.49
Potent, selective and ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK), with IC50 value to be 13 nM for in vitro DNA-PK inhibition; selectivity >100 fold for DNA-PK over related kinases.
KEYWORDS: NU 7441 | supplier | DNA-PK inhibitor | KU 47788 | NU7441 | KU47788 | CAS [503468-95-9] | DNA-RNA | protein kinase | double-strand break | DSB | ATP-competitive | topoisomerase | cell cycle arrest
List of publications using NU 7441 (Axon 1463) purchased from Axon Medchem
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue Spring 2016 Edition
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