IC 87114

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2168

CAS [371242-69-2]

MF C22H19N7O
MW 397.43

  • Purity: 98%
  • Soluble in DMSO

IC 87114


Potent and highly selective small molecule inhibitor of the PI3K p110δ isoform (IC50 values for PI3Kα, β, γ, and δ are >100, 75, 29, and 0.5 μM respectively). IC87114 potently inhibited PIP3 biosynthesis in neutrophils by 60–65% and at 1 μM, it inhibited neutrophil migration by 75% as compared with the control.IC 87114 reduced the infiltration of inflammatory cells into the pancreatic islets and, accordingly, delayed and reduced the loss of glucose homeostasis.
Size Unit Price Stock
5 mg €85.00 In Stock
25 mg €295.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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