MHY 1485

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2425

CAS [326914-06-1]

MF C17H21N7O4
MW 387.39

  • Purity: 99%
  • Soluble in DMSO

MHY 1485


mTOR activator with an inhibitory effect on autophagy. MHY1485 markedly increased the LC3II/LC3I ratio dose-dependently and time-dependently by inhibition of the fusion between autophagosomes and lysosomes, and without increasing the autophagic flux. At 2 µM, MHY1485 did not show any cell death during longer treatment, supporting that MHY1485 had less toxicity than other well-known inhibitors of autophagy. MHY1485 was also tested and found moderately active as antimalarial agent (MIC value of ca. 26 µM against P. Falciparum).
Size Unit Price Stock
10 mg €70.00 In Stock
50 mg €225.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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