GDC 0980 - RG 7422 | GNE 390 | Apitolisib

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1782

CAS [1032754-93-0]

MF C23H30N8O3S
MW 498.60

  • Purity: 99%
  • Soluble in DMSO

GDC 0980

Description

Selective, potent, orally bioavailable inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2) with in vitro IC50 of 5, 27, 7 and 14 nM for p110 α, β, δ and γ isoforms and apparent Ki of 17.3 nM for human mTOR. GDC-0980 has excellent pharmacokinetic and pharmaceutical properties and demonstrates broad activity in xenograft cancer models (breast, ovarian, lung, and prostate)
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Size Unit Price Stock
5 mg €105.00 In Stock
25 mg €350.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €500.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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