KU 0060648 trihydrochloride

Based on 91 reference(s) in Google Scholar 9 10 91

Axon 1584

CAS [881375-00-4]

MF C33H34N4O4S.3HCl
MW 692.10

  • Purity: 99%
  • Soluble in water and DMSO

KU 0060648 trihydrochloride

Description

Potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases.
Product is discontinued (Autumn 2016). 

* The parent molecule of KU 0060648 (Axon 2604) is available online, and makes an excellent alternative for Axon 1584.

KEYWORDS: KU 0060648 trihydrochloride | supplier | DNA-PK inhibitor | KU0060648 HCl | CAS [881375-00-4] | DNA-RNA | DNA-PK | Inhibitor | PIKK | PI3K | cancer | DNA repair | DSB | double-strand breaks

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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