VE 822 - Berzosertib | VX 970

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2452

CAS [1232416-25-9]

MF C24H25N5O3S
MW 463.55

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

VE 822


Selective ATR inhibitor (IC50 values 0.019 µM, 2.6 µM, and 18.1 µM for ATR, ATM, and DNA-PK, respectively) with in vitro and in vivo activity that decreases maintenance of cell-cycle checkpoints and homologous recombination in irradiated cancer cells, and increases persistent DNA damage. VE822 decreased survival of pancreatic cancer cells but not normal cells in response to XRT or gemcitabine.
Size Unit Price Stock
10 mg €110.00 In Stock
50 mg €380.00 In Stock
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Size Unit Price Stock
2 x 10 mg €180.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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