Based on 18 reference(s) in Google Scholar 8 10 18

Axon 4068

CAS [2230820-11-6]

MF C18H20N8O2
MW 380.40

  • Purity: 99%
  • Soluble in DMSO



AZD7648 is an orally available potent and selective next generation DNA-dependent protein kinase (DNA-PK) inhibitor (Enzymatic and Cellular IC50s = 0.6 nM, 91 nM, respectively ), highly selective against a panel of 397 other kinases, including closely-related Kinases such as ATM, ATR, and PI3Kα, β, δ, γ. Exhibits antitumor efficacy either as a monotherapy or in combination with either cytotoxic chemotherapies or novel Anti-Cancer agents.

Keywords: AZD7648 | Supplier | DNA-PK inhibitor | AZD-7648 | AZD 7648 | CT-A7648 | CAS [2230820-11-6] | DNA-RNA | DNA-PK | Inhibitor | Enzymes

DNA-PK inhibitor

Chemical name


Source information

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Parent CAS No.


The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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