AZD7648

Based on 18 reference(s) in Google Scholar 8 10 18

Axon 4068

CAS [2230820-11-6]

MF C18H20N8O2
MW 380.40

  • Purity: 99%
  • Soluble in DMSO

AZD7648

Description

AZD7648 is an orally available potent and selective next generation DNA-dependent protein kinase (DNA-PK) inhibitor (Enzymatic and Cellular IC50s = 0.6 nM, 91 nM, respectively ), highly selective against a panel of 397 other kinases, including closely-related Kinases such as ATM, ATR, and PI3Kα, β, δ, γ. Exhibits antitumor efficacy either as a monotherapy or in combination with either cytotoxic chemotherapies or novel Anti-Cancer agents.

Keywords: AZD7648 | Supplier | DNA-PK inhibitor | AZD-7648 | AZD 7648 | CT-A7648 | CAS [2230820-11-6] | DNA-RNA | DNA-PK | Inhibitor | Enzymes

DNA-PK inhibitor

Chemical name

7-Methyl-2-(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-ylamino)-9-(tetrahydro-2H-pyran-4-yl)-7H-purin-8(9H)-one

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[2230820-11-6]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...