Rapamycin - Sirolimus

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2069

CAS [53123-88-9]

MF C51H79NO13
MW 914.17

  • Purity: 98%
  • Soluble in DMSO



Specific inhibitor of mTOR (mammalian target of Rapamycin); it binds the cytosolic protein FKBP12 and inhibits mTOR pathway by directly binding the mTORC1. Rapamycin selectively inhibits interleukin-2 (IL-2) activation of p70 S6 kinase. It prevents activation of T cells and B cells by inhibiting their response to IL-2. An immunosuppressant drug used to prevent rejection in organ transplantation, especially useful in kidney transplants; also used as a coronary stent coating.

KEYWORDS: Rapamycin | supplier | mTOR inhibitor | Sirolimus | CAS [53123-88-9] | Phosphatidylinositol | mTOR | Inhibitor | Enzymes

Size Unit Price Stock
2 mg €85.00 In Stock
5 mg €125.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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