Rapamycin - Sirolimus

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2069

CAS [53123-88-9]

MF C51H79NO13
MW 914.17

  • Purity: 98%
  • Soluble in DMSO

Rapamycin

Description

Specific inhibitor of mTOR (mammalian target of Rapamycin); it binds the cytosolic protein FKBP12 and inhibits mTOR pathway by directly binding the mTORC1. Rapamycin selectively inhibits interleukin-2 (IL-2) activation of p70 S6 kinase. It prevents activation of T cells and B cells by inhibiting their response to IL-2. An immunosuppressant drug used to prevent rejection in organ transplantation, especially useful in kidney transplants; also used as a coronary stent coating
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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