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CNQX
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C9H4N4O4
- MW: 232.15
Description
Competitive AMPA/kainate receptor antagonist.
The water soluble disodium salt of CNQX (Axon 2522) is available as well
More Information
| Parent CAS No. | 115066-14-3 |
|---|---|
| Chemical Name | 7-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxaline-6-carbonitrile |
| SMILES | C12NC(C(=O)NC1=CC(=C([N+]([O-])=O)C=2)C#N)=O |
| MFCD | MFCD00069232 |
| InChi | InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15) |
| InChiKey | RPXVIAFEQBNEAX-UHFFFAOYSA-N |
| CID | 3721046 |
| Short Description | AMPA/Kainate antagonist |
References
- Honore et al. Quinoxalinediones: Potent competitive non-NMDA glutamate receptor antagonists. Science 1988, 241, 701.
- Long et al. Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, NMDA-, kainate- and quisqualate-mediated depolarization of rat motoneurones in vitro. Br. J. Pharmacol. 1990, 100, 850-854.
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