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CNQX disodium salt
- Parent CAS: 115066-14-3
- Soluble in water and DMSO
- MF: C9H2N4Na2O4
- MW: 276.12
Description
A competitive AMPA/kainate receptor antagonist. Water soluble form of CNQX (Axon 1200)
More Information
| Parent CAS No. | 115066-14-3 |
|---|---|
| Chemical Name | sodium 6-cyano-7-nitroquinoxaline-2,3-bis(olate) |
| SMILES | C12N=C([O-])C([O-])=NC1=CC([N+]([O-])=O)=C(C#N)C=2.[Na+].[Na+] |
| MFCD | N.A. |
| InChi | InChI=1S/C9H4N4O4.2Na/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5;;/h1-2H,(H,11,14)(H,12,15);;/q;2*+1/p-2 |
| InChiKey | YCXDDPGRZKUGDG-UHFFFAOYSA-L |
| CID | 6093155 |
| Short Description | AMPA/Kainate antagonist |
References
- Honore et al. Quinoxalinediones: Potent competitive non-NMDA glutamate receptor antagonists. Science 1988, 241, 701.
- Long et al. Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, NMDA-, kainate- and quisqualate-mediated depolarization of rat motoneurones in vitro. Br. J. Pharmacol. 1990, 100, 850-854.
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