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YM 90K hydrochloride
- Parent CAS: 143151-35-3
- Moderately soluble in DMSO
- MF: C11H7N5O4.HCl
- MW: 309.67
Description
YM 90K hydrochloride is a potent and competitive AMPA receptor antagonist with reported neuroprotective effects.
AMPA receptors mediate fast excitatory glutamatergic neurotransmission and contribute to excitotoxic injury when overactivated. YM 90K is used to study AMPA receptor blockade and neuroprotective mechanisms in CNS models.
Key Features
- AMPA receptor antagonist
- Blocks ionotropic glutamate receptor signaling
- Reported neuroprotective pharmacology
- Useful for excitatory neurotransmission studies
Applications
- AMPA receptor functional assays
- Glutamatergic neurotransmission research
- Excitotoxicity and neuroprotection models
- CNS receptor antagonist profiling
More Information
| Parent CAS No. | 143151-35-3 |
|---|---|
| Chemical Name | 6-Imidazol-1-yl-7-nitro-1,4-dihydro-quinoxaline-2,3-dione hydrochloride |
| SMILES | C1(N2C=CN=C2)C=C2NC(C(=O)NC2=CC=1[N+](=O)[O-])=O.Cl |
| MFCD | MFCD00912163 |
| InChi | InChI=1S/C11H7N5O4.ClH/c17-10-11(18)14-7-4-9(16(19)20)8(3-6(7)13-10)15-2-1-12-5-15;/h1-5H,(H,13,17)(H,14,18);1H |
| InChiKey | UMLFDVOHVJPDIZ-UHFFFAOYSA-N |
| CID | 5486547 |
| Short Description | AMPA antagonist |
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