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Axon 2069
CAS [53123-88-9]
MF C51H79NO13MW 914.17
Specific inhibitor of mTOR (mammalian target of Rapamycin); it binds the cytosolic protein FKBP12 and inhibits mTOR pathway by directly binding the mTORC1. Rapamycin selectively inhibits interleukin-2 (IL-2) activation of p70 S6 kinase. It prevents activation of T cells and B cells by inhibiting their response to IL-2. An immunosuppressant drug used to prevent rejection in organ transplantation, especially useful in kidney transplants; also used as a coronary stent coating.
KEYWORDS: Rapamycin | supplier | mTOR inhibitor | Sirolimus | CAS [53123-88-9] | Phosphatidylinositol | mTOR | Inhibitor | Enzymes
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-ep
[53123-88-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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