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Axon 2511
CAS [1129669-05-1]
MF C22H20FN3O2MW 377.41
GSK-3β inhibitor (IC50 value 53 nM) showing a bell-shaped dose-response relationship. IM12 enhances canonical Wnt signalling, and attenuates cell proliferation and neuronal differentiation of human neural progenitor cells with similar potency as SB 216763 (Axon 1303).
*Promotion: IM 12 is an important componant of Inhibitor Set(s):
KEYWORDS: IM 12 | supplier | GSK-3β inhibitor | IM12 | [1129669-05-1] | GSK3 | canonical | Wnt | PKC | cell proliferation | neuronal differentiation | neural progenitor cells | NPCs
3-(4-fluorophenethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
[1129669-05-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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