CNS

The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.

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Axon ID Name Description From price
1066 N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide MAO inhibitor €95.00
1064 Prop-2-ynyl-2-aminotetraline hydrochloride Dopamine agonist Inquire
2534 (+)-Azasetron hydrochloride 5-HT3 antagonist €135.00
1077 (+)-Epibatidine dihydrochloride Nicotinic acetylcholine receptor agonist €155.00
1107 (+)-MDL 105725 5-HT2A antagonist €130.00
1594 (+)-Pagoclone GABAA-α2 and GABAA-α3 agonist €135.00
1073 (+)-PD 128907 hydrochloride D3 agonist €120.00
1071 (+)-PHNO hydrochloride D2 agonist €110.00
2535 (-)-Azasetron hydrochloride 5-HT3 antagonist €135.00
1078 (-)-Epibatidine dihydrochloride Nicotinic acetylcholine receptor agonist €155.00
1108 (-)-MDL 105725 5-HT2A antagonist Inquire
1092 (-)-NPPCC 5-HT1A agonist Inquire
1074 (-)-PD 128907 hydrochloride D3 agonist €135.00
1359 (-)-WAY 100135 dihydrochloride 5-HT1A antagonist €95.00
1049 (R)-(+)-5-methoxy-2-aminotetraline hydrochloride Dopamine agonist Inquire
1013 (R)-(+)-7-Hydroxy-DPAT hydrobromide D3 agonist Inquire
1030 (R)-(+)-7-Methoxy-N-propyl-2-aminotetraline hydrochloride Building Block; unknown pharmacology €225.00
1016 (R)-(+)-8-Hydroxy-DPAT hydrobromide 5-HT1A agonist €105.00
1058 (R)-(+)-8-Methoxy-2-aminotetraline hydrochloride Building Block; 5-HT1A agonist Inquire
1758 (R)-(+)-BAY K 8644 Calcium (Ca2+) channel modulator €115.00
1714 (R)-(+)-SLV 319 Inactive enantiomer of SLV 319 €95.00
1309 (R)-(-)-BMS 204352 Potassium channel opener; Less active enantiomer of Axon 1112 €145.00
1095 (R)-(-)-LY 426965 dihydrochloride 5-HT1A antagonist €115.00
2784 (R)-(-)-N-Desmethyl-PK 11195 Radioligand precursor of the benzodiazepine antagonist (R)-(-)-PK 11195 €145.00
2785 (R)-(-)-PK 11195 Benzodiazepine antagonist. €125.00
1229 (R)-(-)-Rolipram PDE4 inhibitor €110.00
1007 (R)-5-Hydroxy-DPAT hydrobromide D2 antagonist €145.00
1026 (R)-5-Methoxy-N-propyl-2-aminotetraline hydrochloride Dopamine agonist Inquire
1010 (R)-6-Hydroxy-DPAT hydrobromide Dopamine agonist Inquire
1997 (R)-6-Hydroxybuspirone hydrochloride 5-HT1A partial agonist €105.00

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