CNS
The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.
Axon ID | Name | Description | From price | |
---|---|---|---|---|
1066 | N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide | MAO inhibitor | €95.00 | |
1064 | Prop-2-ynyl-2-aminotetraline hydrochloride | Dopamine agonist | Inquire | |
2534 | (+)-Azasetron hydrochloride | 5-HT3 antagonist | €135.00 | |
1077 | (+)-Epibatidine dihydrochloride | Nicotinic acetylcholine receptor agonist | €155.00 | |
1107 | (+)-MDL 105725 | 5-HT2A antagonist | €130.00 | |
1594 | (+)-Pagoclone | GABAA-α2 and GABAA-α3 agonist | €135.00 | |
1073 | (+)-PD128907 hydrochloride | D3 agonist | €120.00 | |
1071 | (+)-PHNO hydrochloride | D2 agonist | €110.00 | |
2535 | (-)-Azasetron hydrochloride | 5-HT3 antagonist | €135.00 | |
1078 | (-)-Epibatidine dihydrochloride | Nicotinic acetylcholine receptor agonist | €155.00 | |
1108 | (-)-MDL 105725 | 5-HT2A antagonist | Inquire | |
1092 | (-)-NPPCC | 5-HT1A agonist | Inquire | |
1074 | (-)-PD128907 hydrochloride | D3 agonist | Inquire | |
1359 | (-)-WAY 100135 dihydrochloride | 5-HT1A antagonist | €95.00 | |
1049 | (R)-(+)-5-methoxy-2-aminotetraline hydrochloride | Dopamine agonist | Inquire | |
1013 | (R)-(+)-7-Hydroxy-DPAT hydrobromide | D3 agonist | Inquire | |
1030 | (R)-(+)-7-Methoxy-N-propyl-2-aminotetraline hydrochloride | Building Block; unknown pharmacology | €225.00 | |
1016 | (R)-(+)-8-Hydroxy-DPAT hydrobromide | 5-HT1A agonist | €105.00 | |
1058 | (R)-(+)-8-Methoxy-2-aminotetraline hydrochloride | Building Block; 5-HT1A agonist | Inquire | |
1758 | (R)-(+)-BAY K 8644 | Calcium (Ca2+) channel modulator | €115.00 | |
1714 | (R)-(+)-SLV 319 | Inactive enantiomer of SLV 319 | €95.00 | |
1309 | (R)-(-)-BMS 204352 | Potassium channel opener; Less active enantiomer of Axon 1112 | €145.00 | |
1095 | (R)-(-)-LY 426965 dihydrochloride | 5-HT1A antagonist | €115.00 | |
2784 | (R)-(-)-N-Desmethyl-PK 11195 | Radioligand precursor of the benzodiazepine antagonist (R)-(-)-PK 11195 | €145.00 | |
2785 | (R)-(-)-PK 11195 | Benzodiazepine antagonist. | €125.00 | |
1229 | (R)-(-)-Rolipram | PDE4 inhibitor | €110.00 | |
1007 | (R)-5-Hydroxy-DPAT hydrobromide | D2 antagonist | €145.00 | |
1026 | (R)-5-Methoxy-N-propyl-2-aminotetraline hydrochloride | Dopamine agonist | Inquire | |
1010 | (R)-6-Hydroxy-DPAT hydrobromide | Dopamine agonist | Inquire | |
1997 | (R)-6-Hydroxybuspirone hydrochloride | 5-HT1A partial agonist | €105.00 |