Bulk Inquiry
(R)-5-Hydroxy-DPAT hydrobromide
- (R)-5-OH-DPAT
Axon 1007
- Parent CAS: 69367-51-7
- Optical Purity: >98% e.e.
- Soluble in DMSO
- MF: C16H25NO.HBr
- MW: 328.29
Description
While racemic 5-OH-DPAT (Axon 1006) is a potent and selective dopamine (DA) D2-receptor agonist, its R-enantiomer, (R)-5-OH DPAT is a weakly potent DA D2-receptor antagonist
More Information
| Parent CAS No. | 69367-51-7 |
|---|---|
| Chemical Name | (R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol hydrobromide |
| SMILES | C1C=C2C[C@H](N(CCC)CCC)CCC2=C(O)C=1.Br |&1:4,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1 |
| InChiKey | QHPNEGRNHVBQOB-PFEQFJNWSA-N |
| CID | 91826431 |
| Short Description | D2 antagonist |
References
- A Karlsson et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): Assessment of optical purities and dopaminergic activities. Chirality. 1989-1995, 2(2), 90-95.
- S.L. Payne et al. Mechanisms of ligand binding and efficacy at the human D2(short) dopamine receptor. J. Neurochem. 2002, 82, 1106–1117.
Related Products
Other Categories
Get a Quote for
Loading...