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ST 148
Axon 1342
- Parent CAS: 390803-39-1
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C27H36N4O3S.C4H4O4
- MW: 612.74
Description
ST 148 is a dopamine D2 receptor antagonist with improved selectivity for human D2L receptors.
D2L receptors participate in dopaminergic regulation of motor control, reward circuitry, endocrine signaling and antipsychotic-relevant CNS pathways. ST 148 is useful for D2L-selective antagonist studies.
Key Features
- Dopamine D2 receptor antagonist
- Improved selectivity for hD2L receptors
- Useful for D2 receptor subtype pharmacology
- Relevant to CNS dopaminergic pathway research
Applications
- D2 receptor binding and functional assays
- D2L selectivity profiling
- Dopaminergic signaling studies
- Antipsychotic mechanism research
More Information
| Parent CAS No. | 390803-39-1 |
|---|---|
| Chemical Name | 5-Dimethylamino-naphthalene-1-sulfonic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide maleate |
| SMILES | C1C=C(N2CCN(CCCCNS(=O)(=O)C3C=CC=C4C(N(C)C)=CC=CC=34)CC2)C(OC)=CC=1.C(/C(=O)O)=C/C(=O)O |
| MFCD | MFCD04040023 |
| InChi | InChI=1S/C27H36N4O3S.C4H4O4/c1-29(2)24-13-8-11-23-22(24)10-9-15-27(23)35(32,33)28-16-6-7-17-30-18-20-31(21-19-30)25-12-4-5-14-26(25)34-3;5-3(6)1-2-4(7)8/h4-5,8-15,28H,6-7,16-21H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChiKey | NMWGXMJVHMDGSA-BTJKTKAUSA-N |
| CID | 11957682 |
| Short Description | D2 antagonist |
ST 148
dopamine D2 receptor antagonist
ST148
DRD2
dopamine D2 receptor
D2
Antagonist
dopamine signaling
D2 receptor binding and functional assays
D2L selectivity profiling
Dopaminergic signaling studies
Antipsychotic mechanism research
addiction research
GPCR pharmacology
receptor selectivity
signal transduction
receptor pharmacology
CNS
CAS 390803-39-1
CAS 390803-40-4
Axon Medchem
Axon 1342
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