(±)-PHNO hydrochloride
Axon 1070
- Parent CAS: 88058-85-9
Purity:
98%
- Soluble in water and DMSO
- MF: C15H21NO2.HCl
- MW: 283.79
Description
(±)-PHNO hydrochloride is the racemic form of PHNO, a potent and selective dopamine D2 receptor agonist. It is used to activate D2 receptor-mediated GPCR signaling and to compare racemic PHNO activity with the more active (+)-enantiomer (Axon 1071).
PHNO-based ligands are important tools in dopamine receptor pharmacology and radiotracer development. (±)-PHNO hydrochloride supports studies of D2 agonism, stereoselective ligand activity and dopaminergic receptor functional responses.
Key Features
- Potent dopamine D2 receptor agonist
- Racemic PHNO reference ligand
- Activates dopamine D2 receptor-mediated GPCR signaling
- Useful for comparison with enantiopure (+)-PHNO
Applications
- Dopamine D2 receptor activation assays
- Dopaminergic GPCR pharmacology
- Stereoselective ligand comparison studies
- Radiotracer and receptor occupancy research
More Information
| Parent CAS No. | 88058-85-9 |
|---|---|
| Chemical Name | trans-(+/-)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol hydrochloride |
| MFCD | MFCD10565901 |
| Short Description | D2 agonist |
(±)-PHNO hydrochloride
potent dopamine D2 receptor agonist
PHNO
DRD2
dopamine D2 receptor
D2
Agonist
GPCR signaling
dopamine signaling
Dopamine D2 receptor activation assays
Dopaminergic GPCR pharmacology
Stereoselective ligand comparison studies
Radiotracer and receptor occupancy research
GPCR pharmacology
receptor selectivity
signal transduction
receptor pharmacology
GPCR
CAS 88058-89-3
CAS 100935-99-7
Axon Medchem
Axon 1070
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