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ABT 724 trihydrochloride

Axon 1250

Parent CAS: 70006-24-5

Purity: 99%

Soluble in water

MF: C17H19N5.3HCl
MW: 402.75

Description

ABT 724 trihydrochloride is a selective dopamine D4 receptor partial agonist.

D4 receptors are Gi/o-coupled dopamine receptors implicated in cognition, reward processing, cortical signaling and neuropsychiatric research. ABT 724 is useful for selectively probing D4 receptor activation without full agonist efficacy.

Key Features

Dopamine D4 receptor partial agonist
Activates D4 signaling with partial efficacy
Useful for dopaminergic receptor subtype research
Relevant to CNS and behavioral pharmacology studies

Applications

D4 receptor functional assays
Dopamine receptor selectivity profiling
CNS dopaminergic signaling studies
Partial agonist pharmacology models

More Information

Certificate of Analysis (B2)

Material Safety Data Sheet (B2)

Certificate of Analysis

Material Safety Data Sheet

Parent CAS No.	70006-24-5
Chemical Name	2-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-1H-benzoimidazole trihydrochloride
SMILES	C1(N2CCN(CC3NC4C=CC=CC=4N=3)CC2)N=CC=CC=1.Cl.Cl.Cl
MFCD	MFCD08703101
InChi	InChI=1S/C17H19N5.3ClH/c1-2-6-15-14(5-1)19-16(20-15)13-21-9-11-22(12-10-21)17-7-3-4-8-18-17;;;/h1-8H,9-13H2,(H,19,20);3*1H
InChiKey	AZFUVPBLKQGSRI-UHFFFAOYSA-N
CID	16759165
Short Description	D4 agonist

ABT 724 trihydrochloride dopamine D4 receptor partial agonist ABT724 ABT-724 DRD4 dopamine D4 receptor D4 Partial agonist Agonist dopamine signaling D4 receptor functional assays Dopamine receptor selectivity profiling CNS dopaminergic signaling studies Partial agonist pharmacology models cognition behavioral neuroscience addiction research receptor selectivity signal transduction CNS CAS 70006-24-5 CAS 587870-77-7 Axon Medchem Axon 1250 Supplier Vendor

References

Brioni et al. Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats. Proc. Natl. Acad. Sci. USA 2004. 101, 6758.

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ABT 724 trihydrochloride

Description

Key Features

Applications

More Information

Certificate of Analysis

Material Safety Data Sheet

References

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Other Categories

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