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B-HT 920 dihydrochloride

 - Talipexole
Axon 1153
  • Parent CAS:  101626-70-4
Purity:  99%
  • Soluble in water and DMSO
  • MF:  C10H15N3S.2HCl
  • MW:  282.23

Description

B-HT 920 dihydrochloride (Talipexole) is a multi-target ligand described as a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist. It is useful for studying cross-talk between dopaminergic, adrenergic and serotonergic pathways.

B-HT 920 dihydrochloride has a pharmacological profile that spans GPCR activation and serotonin ion channel antagonism. It is suitable for experiments that require careful interpretation of D2, α2 and 5-HT3-mediated effects.

Key Features

  • Dopamine D2 receptor agonist
  • α2-adrenoceptor agonist
  • 5-HT3 receptor antagonist
  • Multi-target CNS receptor ligand

Applications

  • D2 receptor pharmacology
  • α2-adrenoceptor signaling studies
  • 5-HT3 antagonist assays
  • Multi-receptor CNS pathway research

More Information

Parent CAS No. 101626-70-4
Chemical Name 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-ylamine dihydrochloride
SMILES C12N=C(SC=1CCN(CC=C)CC2)N.Cl.Cl
MFCD MFCD00274573
InChi InChI=1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8;;/h2H,1,3-7H2,(H2,11,12);2*1H
InChiKey DPQAXNSOFFYKDS-UHFFFAOYSA-N
CID 104870
Short Description α2 and D2 agonist

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