Dopamine receptors (GPCR-A17) are widespread in the body of vertebrates, playing major roles in processes of the central nervous system, as well as in the periphery. In the CNS, dopaminergic neurons are critically  involved in voluntary movement, memory, learning, sleep, attention, feeding, and rewarding, Well known examples of disorders as a result of malfunction of the central dopaminergic system are Parkinson’s disease (loss of striatal dopaminergic innervations in the brain), schizophrenia, depression, ADHD, and addiction (among many others). In the periphery, dopamine plays important physiological roles in the regulation of olfaction, retinal processes, hormonal regulation, cardiovascular functions, sympathetic regulation, immune system, renal functions, and more[1]. Five major classes (D1-D5) have been identified thus far, which can be grouped into two sub classes. The group of D1-like receptors (members D1 and D5; all stimulating the second messenger system adenylate cyclase), and the group of D2-like receptors (members D2, D3 and D4; all inhibiting adenylate cyclase). As widespread and abundant as  dopaminergic neurons are in the body of vertebrates, as comprehensive and diverse is the list of Axon LigandsTM interacting at all subtypes of dopaminergic receptors (selectively, or specific combinations).

[1] The Physiology, Signaling, and Pharmacology of Dopamine Receptors. J-M Beaulieu, R.R. Gainetdinov. Pharmacol. Rev. 2011, 63, 182-217.

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Axon ID Name Description From price
1064 Prop-2-ynyl-2-aminotetraline hydrochloride Dopamine agonist Inquire
1073 (+)-PD128907 hydrochloride D3 agonist €120.00
1071 (+)-PHNO hydrochloride D2 agonist €110.00
1074 (-)-PD128907 hydrochloride D3 agonist Inquire
1049 (R)-(+)-5-methoxy-2-aminotetraline hydrochloride Dopamine agonist Inquire
1013 (R)-(+)-7-Hydroxy-DPAT hydrobromide D3 agonist Inquire
1007 (R)-5-Hydroxy-DPAT hydrobromide D2 antagonist €145.00
1026 (R)-5-Methoxy-N-propyl-2-aminotetraline hydrochloride Dopamine agonist Inquire
1010 (R)-6-Hydroxy-DPAT hydrobromide Dopamine agonist Inquire
1055 (R)-7-Methoxy-2-aminotetraline hydrochloride Dopamine agonist €125.00
1036 (R)-PPHT hydrochloride (R)-enantiomer of PPHT (Axon 1035); D2 agonist Inquire
1050 (S)-(-)-5-methoxy-2-aminotetraline hydrochloride Dopamine agonist €145.00
1014 (S)-(-)-7-Hydroxy-DPAT hydrochloride D3 agonist €115.00
1008 (S)-5-Hydroxy-DPAT hydrobromide D2 agonist €145.00
1027 (S)-5-Methoxy-N-propyl-2-aminotetraline hydrochloride Dopamine agonist Inquire
1011 (S)-6-Hydroxy-DPAT hydrobromide Dopamine agonist Inquire
1037 (S)-PPHT hydrochloride (S)-enantiomer of PPHT (Axon 1035); D2 agonist Inquire
1072 (±)-PD128907 hydrochloride D3 agonist €95.00
1070 (±)-PHNO hydrochloride D2 agonist; racemate of PHNO (Axon 1071) Inquire
1047 3-(Dipropylamino)-3,4-dihydro-2H-1-benzopyran-8-ol hydrochloride Dopamine agonist Inquire
1002 3-[2-(Diproplyamino)ethyl]phenol hydrobromide Dopamine agonist €95.00
1044 5,6-Dihydroxy-2-aminotetraline hydrobromide Dopamine agonist Inquire
1019 5,6-Dihydroxy-N-methyl-N-propyl-aminotetraline hydrochloride Dopamine agonist Inquire
1006 5-Hydroxy-DPAT hydrobromide D2 agonist €105.00
1048 5-Methoxy-2-aminotetraline hydrochloride Dopamine agonist Inquire
1045 6,7-Dihydroxy-2-aminotetraline hydrobromide Dopamine agonist €125.00
1021 6,7-Dihydroxy-N-methyl-N-propyl-aminotetraline hydrobromide Dopamine agonist Inquire
1043 6,7-Dimethoxy-2-aminotetraline hydrobromide Dopamine agonist €125.00
1009 6-Hydroxy-DPAT hydrobromide Dopamine agonist Inquire
1012 7-Hydroxy-DPAT hydrobromide D3 agonist €60.00

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