Wnt-C59 - C59

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2287

CAS [1243243-89-1]

MF C25H21N3O
MW 379.45

  • Purity: 98%
  • Soluble in DMSO



Nanomolar and orally available inhibitor of mammalian PORCN acyltransferase activity (IC50 value of 74 pM) that blocks activation of all evaluated human Wnts ( Wnt palmitoylation, Wnt interaction with the carrier protein Wntless/WLS, Wnt secretion, and Wnt activation of β-catenin reporter activity).The tumor growth inhibition of Wnt-C59 in MMTV-WNT1 transgenic mice is associated with decreased Wnt/β-catenin signaling in tumors.
Size Unit Price Stock
2 mg €75.00 In Stock
5 mg €105.00 In Stock
25 mg €365.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €540.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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