Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2212

CAS [1427782-89-5]

MF C25H20N4O2S2
MW 472.58

  • Purity: 99%
  • Soluble in DMSO



Highly potent porcupine inhibitor (Porcn; EC50 value 0.5 nM), a membrane-bound O-acyltransferase (MBOAT); Wnt signaling inhibitor; 60-times more potent than IWP-2.IWP-L6 effectively inhibits posterior axis formation and resected tailfin regeneration in juvenile zebrafish at low micromolar concentrations. IWP L6 specifically and reversibly blocks Wnt signaling and Wnt mediated branching morphogenesis in cultured mouse embryonic kidneys. Stable in human plasma over 24 h.
Highly potent porcupine (Porcn) inhibitor

Chemical name


Parent CAS No.


Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €450.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €200.00 In Stock
2 x 50 mg €720.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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