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BIO - GSK-3 inhibitor IX | 6-Bromoindirubin-3'-oxime

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1693

CAS [667463-62-9]

MF C16H10BrN3O2
MW 356.17

  • Purity: 98%
  • Soluble in DMSO

BIO

Description

Potent, reversible, ATP-competitive and selective inhibitor of glycogen synthase kinase GSK-3 (IC50: 5 nM); Inhibition of GSK by BIO results in the activation of the Wnt signaling pathway and sustained pluripotency in human and murine embryonic stem cells (ESCs). BIO is shown to maintain self-renewal in human and murine ESCs
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10 mg €90.00 In Stock
50 mg €300.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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