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- GSK-3 inhibitor IX - 6-Bromoindirubin-3'-oxime- Soluble in DMSO
- MF: C16H10BrN3O2
- MW: 356.17
Description
More Information
| Parent CAS No. | 667463-62-9 |
|---|---|
| Chemical Name | (Z)-6'-Bromo-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime |
| SMILES | C1C=C2/C(=NO)/C(/NC2=CC=1)=C1C2C=CC(Br)=CC=2NC1=O |
| MFCD | MFCD08705318 |
| InChi | InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,18,22H,(H,19,21)/b15-13-,20-14+ |
| InChiKey | DDLZLOKCJHBUHD-WAVHTBQISA-N |
| CID | 448949 |
| Short Description | GSK-3 inhibitor |
References
- N Sato et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nature Med. 2004, 10(1), 55-63.
- L Meijer et al. GSK-3-selective inhibitors derived from tyrian purple indirubins. Chem. Biol. 2003, 10, 1255-1266.
- AS Tseng et al. The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes. Chem. Biol. 2006, 13, 957.
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