ICG 001

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1766

CAS [847591-62-2]

MF C33H32N4O4
MW 548.63

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

ICG 001

Description

Specific inhibitor of Wnt/β-catenin signaling pathway; inhibiting β-catenin/cyclic AMP response element-binding (CREB) protein transcription. ICG-001 selectively induces apoptosis in transformed cells but not in normal colon cells, reduces in vitro growth of colon carcinoma cells, and is efficacious in the Min mouse and nude mouse xenograft models of colon cancer
Specific inhibitor of Wnt/β-catenin signaling pathway

Chemical name

(6S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxooctahydro-1H-pyrimido[1,2-a]pyrazine-1-carboxamide

Parent CAS No.

[780757-88-2 (relative stereochemistry; Scifinder names incorrectly) 847591-62-2 (absolute stereochemistry)]

Order
Size Unit Price Stock
5 mg €115.00 In Stock
25 mg €405.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €620.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...