Oxidoreductases

Oxidoreductases (EC 1.) comprise the large class of enzymes that catalyze biological oxidation/reduction reactions. They play an important role in both aerobic and anaerobic metabolism.  They can be found in glycolysis, TCA cycle, oxidative phosphorylation, and in amino acid metabolism. Subcategories within this class of biological targets are created based the kind of acceptor molecules involved in the redox reaction they catalyze, and on and the nature of their substrates[1].


[1] Enzyme Nomenclature 1992. Academic Press,San Diego,California, ISBN 0-12-227164-5.

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Axon ID Name Description From price
1066 N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide MAO inhibitor €95.00
2989 15-LOX-1 inhibitor i472 Inhibitor of 15-lipoxygenase-1 (15-LOX-1) €170.00
1873 Abiraterone Inhibitor of CYP17A1 €90.00
1874 Abiraterone acetate Prodrug of Abiraterone; Inhibitor of CYP17A1 €90.00
2746 AG-120 IDH1 mutant enzyme inhibitor €125.00
2745 AG-221 IDH2 mutant enzyme inhibitor €95.00
2122 AGI 5198 Inhibitor of R132 mutant isocitrate dehydrogenase 1 (IDH1) €60.00
2274 AGI 6780 Potent and selective inhibitor of the tumor-associated mutant IDH2 (R140Q) €90.00
2551 Alda 1 Small molecule activator of ALDH2 €65.00
3316 Anastrozole Potent, highly selective, and orally active aromatase inhibitor €50.00
2883 APPA Aldose reductase inhibitor €105.00
2819 APX-115 First-in-class pan-NADPH oxidase (Nox) inhibitor €125.00
2787 ASP 9521 Inhibitor of 17 β–hydroxysteroid dehydrogenase type 5 €75.00
2288 ATB 346 Orally active hydrogen sulfide-releasing cyclooxygenase inhibitor €110.00
2043 Atorvastatin calcium Inhibitor of HMG-CoA reductase €60.00
3943 AVN944 Incompetitive small molecule inhibitor of inosine monophosphate dehydrogenase (IMPDH) Inquire
3863 BAY-1436032 Highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) Inquire
3638 BAY-179 Potent, selective, and species cross-reactive complex I inhibitor €100.00
2306 Bizine Potent LSD1 inhibitor with selectivity over MAO-A/B, and LSD2 €120.00
3479 BN80933 Potent antioxidant and selective nNOS inhibitor €150.00
2489 Brassinin Dual IDO1/STAT3 inhibitor with antifungal and anticancer activity €75.00
2698 BTZ043 Antimycobacterial DprE1 inhibitor that kills Mycobacterium tuberculosis €105.00
1756 BVT 2733 hydrochloride Inhibitor of 11β-hydroxysteroid dehydrogenase type 1 €90.00
2585 CBR 5884 Noncompetitive inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) €90.00
1919 Celecoxib Selective COX-2 inhibitor €50.00
3163 Clotrimazole Fungal CYP450 enzyme 14α-demethylase inhibitor €50.00
2622 CPI 4203 Selective inhibitor of KDM5 demethylases (H3K4 specific) €85.00
2573 CPI 455 Selective inhibitor of KDM5 demethylases (H3K4 specific) €95.00
2125 CPI-613 Inhibitor of mitochondrial pyruvate dehydrogenase (PDH) complex €110.00
3725 CVT-10216 Highly selective, reversible inhibitor of ALDH-2 €110.00

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