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EBPC
Axon 1204
CAS:
4450-98-0
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C14H15NO4
- MW: 261.27
Description
Potent aldose reductase inhibitor
More Information
| Parent CAS No. | 4450-98-0 |
|---|---|
| Chemical Name | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester |
| SMILES | C1C=C(CN2CC(C(OCC)=O)=C(O)C2=O)C=CC=1 |
| MFCD | MFCD00179167 |
| InChi | InChI=1S/C14H15NO4/c1-2-19-14(18)11-9-15(13(17)12(11)16)8-10-6-4-3-5-7-10/h3-7,16H,2,8-9H2,1H3 |
| InChiKey | IGYRPDIWSYGHMY-UHFFFAOYSA-N |
| CID | 54677973 |
| Short Description | Aldose reductase inhibitor |
References
- EK Lee et al. Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases. Anti-Cancer Drugs. 2002, 13(8), 859-868.
- BL Mylari et al. A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate and its congeners. J. Med. Chem. 1991, 34, 1011.
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