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Niraxostat

 - Y700  - Piraxostat
Axon 1174
CAS:  206884-98-2
Purity:  99%
  • Soluble in DMSO
  • MF:  C16H17N3O3
  • MW:  299.32

Description

Niraxostat (also known as Y-700 or Piraxostat) is an orally active, potent xanthine oxidoreductase inhibitor (XOR). By inhibiting the enzyme responsible for converting hypoxanthine to xanthine and subsequently to uric acid, it effectively reduces serum uric acid levels.

Xanthine oxidase catalyzes uric acid production during purine metabolism and is a key target in hyperuricemia and gout research. Niraxostat is useful for studying XO inhibition, urate-lowering mechanisms and purine metabolism.

Key Features

  • Xanthine oxidase inhibitor
  • Reported to reduce serum uric acid levels potently
  • Orally bioavailable urate-lowering research compound
  • Relevant for gout and hyperuricemia pathway studies

Applications

  • Xanthine oxidase inhibition assays
  • Gout and hyperuricemia research
  • Purine metabolism studies
  • Uric acid lowering pathway models

More Information

Certificate of Analysis (B2)
Material Safety Data Sheet (B2)

Certificate of Analysis

B1

Material Safety Data Sheet

B1
Parent CAS No. 206884-98-2
Chemical Name 1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyrazole-4-carboxylic acid
SMILES C1C=C(OCC(C)(C)C)C(C#N)=CC=1N1N=CC(C(O)=O)=C1
MFCD MFCD09955279
InChi InChI=1S/C16H17N3O3/c1-16(2,3)10-22-14-5-4-13(6-11(14)7-17)19-9-12(8-18-19)15(20)21/h4-6,8-9H,10H2,1-3H3,(H,20,21)
InChiKey AETHRPHBGJAIBT-UHFFFAOYSA-N
CID 449035
Short Description XO inhibitor

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