MAO
Mono-amine oxidases (MAO; EC 1.4.3.x) play an important role in neurotransmitter metabolism. Inhibitors of this class of enzymes have played a major role in our understanding of the functional roles of dopamine (DA), norepinephrine (NE), and serotonin (5-HT) neurotransmission in the CNS. However, due to their potentially lethal dietary and drug interactions (“cheese effect”), monoamine oxidase inhibitors have historically been reserved as a last-in-line treatment of psychiatric disorders, only to be used when other classes of antidepressant drugs have failed[1].
[1] http://www.mayoclinic.com/health/depression/DS00175/DSECTION=treatments-and-drugs
Axon ID | Name | Description | From price | |
---|---|---|---|---|
1066 | N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide | MAO inhibitor | €95.00 | |
3629 | Moclobemide | Reversible and selective MAO-A inhibitor; Antidepressant | €70.00 | |
1022 | N 0425 hydrochloride | MAO inhibitor | €95.00 | |
1062 | N 0425 hydrochloride, (+)- | MAO inhibitor | €135.00 | |
1063 | N 0425 hydrochloride, (-)- | MAO inhibitor | €135.00 | |
1018 | N 0430 hydrobromide | MAO inhibitor; Dopamine agonist | €115.00 | |
1020 | N 0432 hydrobromide | MAO inhibitor; Dopamine agonist | Inquire | |
1067 | N-Cyclopropyl-2-Aminotetraline hydrochloride | MAO inhibitor | Inquire | |
3332 | R-(-)-Deprenyl hydrochloride | Highly selective MAO-B inhibitor | €50.00 | |
2629 | TB5 | Competitive and reversible MAO-B inhibitor capable of crossing the BBB | €105.00 | |
2977 | Toloxatone | Reversible MAO-A inhibitor; Antidepressant | €80.00 |