Dehydrogenases

A dehydrogenase enzyme (a.k.a. DHO) is an enzyme belonging to the group of oxidoreductases (EC 1.) that oxidizes a substrate by a reduction reaction that transfers one or more hydrides (H) to an electron acceptor, usually NAD+/NADP+ or a flavincoenzyme such as FAD or FMN.

23 Item(s)

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Axon ID Name Description From price
2125 6,8-Bis(benzylthio)octanoic acid Inhibitor of mitochondrial pyruvate dehydrogenase (PDH) complex €105.00
2746 AG-120 IDH1 mutant enzyme inhibitor €125.00
2745 AG-221 IDH2 mutant enzyme inhibitor €95.00
2122 AGI 5198 Inhibitor of R132 mutant isocitrate dehydrogenase 1 (IDH1) €60.00
2274 AGI 6780 Potent and selective inhibitor of the tumor-associated mutant IDH2 (R140Q) €90.00
2551 Alda 1 Small molecule activator of ALDH2 €65.00
2787 ASP 9521 Inhibitor of 17 β–hydroxysteroid dehydrogenase type 5 €75.00
2698 BTZ043 Antimycobacterial DprE1 inhibitor that kills Mycobacterium tuberculosis €105.00
1756 BVT 2733 hydrochloride Inhibitor of 11β-hydroxysteroid dehydrogenase type 1 €90.00
2585 CBR 5884 Noncompetitive inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) €90.00
2476 DEAB Potent inhibitor of cytosolic (class 1) aldehyde dehydrogenase (ALDH) enzymes €50.00
3020 DS44960156 Selective MTHFD2 inhibitor €160.00
3621 GSK2837808A Potent, selective and NADH-competitive inhibitor of LDH-A €130.00
2909 IACS-010759 Potent and orally bioavailable inhibitor of complex I of oxidative phosphorylation €95.00
2654 JK184 Hedgehog (Hh) signaling pathway antagonist with antiproliferative activity €80.00
3164 Leflunomide Selective inhibitor of de novo pyrimidine synthesis; DMARD €60.00
2480 LW6 Inhibitor of HIF-1α stability via MDH2 inhibition and/or binding with CHP1 €85.00
2623 NCT-503 PHGDH inhibitor that suppresses the growth of PHGDH-dependent cancer cells €105.00
2450 NHI 2 Selective cell membrane permeable inhibitor of human lactate dehydrogenase A €90.00
2626 PBTZ169 Potent irreversible DprE1 inhibitor; tuberculosis therapeutic €95.00
1515 Sitamaquine Succinate dehydrogenase inhibitor with anti-Leishmanial activity €120.00
3317 Trilostane Orally active, competitive inhibitor of 3β-hydroxysteroid dehydrogenase €90.00
2377 Vidofludimus Oral immunomodulatory drug that inhibits dihydroorotate dehydrogenase (DHODH) €125.00

23 Item(s)

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