Tyrosinase

Tyrosinase

Tyrosinases (EC 1.14.18.1) catalyze the oxidations of both monophenols (cresolase or monophenolase activity) and o-diphenols (catecholase or diphenolase activity) into reactive o-quinones. Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, and it is the key protein involved in mammalian melanogenesis and is responsible for enzymatic browning reactions in damaged fruits during post-harvest handling and processing. In view of its role in pigmentation, tyrosinase inhibitors have become increasingly important in the cosmetic and medicinal products used in the prevention of hyperpigmentaion (due to UV radiation).

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  • MHY 908
    2402
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  • Tyrosinase inhibitor compound 2-06
    4251
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    From $132.00

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More About Tyrosinase

Tyrosinases (EC 1.14.18.1) catalyze the oxidations of both monophenols (cresolase or monophenolase activity) and o-diphenols (catecholase or diphenolase activity) into reactive o-quinones.  Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, and it is the key protein involved in mammalian melanogenesis and is responsible for enzymatic browning reactions in damaged fruits during post-harvest handling and processing[1]. In view of its role in pigmentation, tyrosinase inhibitors have become increasingly important in the cosmetic and medicinal products used in the prevention of hyperpigmentaion (due to UV radiation)[2].


[1] T.S. Chang. An updated review of tyrosinase inhibitors. Int J Mol Sci. 2009 May 26;10(6):2440-75.
[2] M.T.H. Khan. Molecular design of tyrosinase inhibitors: A critical review of promising novel inhibitors from synthetic origins. Pure Appl. Chem., 2007, 79, 12, 2277-2295.

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