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PPHT hydrochloride
- N 0434
Axon 1035
- Parent CAS: 87857-27-0
Purity:
98%
- Soluble in water and DMSO
- MF: C21H27NO.HCl
- MW: 345.91
Description
PPHT hydrochloride is a very potent and specific dopamine D2 receptor agonist. It is used as a dopaminergic reference ligand for experiments that require selective activation of D2 receptor-mediated GPCR signaling.
D2 receptors regulate motor control, reward circuitry, endocrine signaling and neuronal excitability. PPHT hydrochloride is suitable for receptor binding and functional assays focused on D2 receptor pharmacology and dopaminergic pathway activation.
Key Features
- Very potent dopamine D2 receptor agonist
- Specific dopaminergic research ligand
- Activates D2 receptor-mediated GPCR signaling
- Useful reference compound for D2 functional assays
Applications
- Dopamine D2 receptor pharmacology
- Dopaminergic GPCR signaling studies
- Functional agonist-response assays
- CNS receptor research and ligand comparison studies
More Information
| Parent CAS No. | 87857-27-0 |
|---|---|
| Chemical Name | 6-(Phenethyl(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride |
| SMILES | C1C=C2CC(N(CCC)CCC3C=CC=CC=3)CCC2=C(O)C=1.Cl |
| MFCD | MFCD00055157 |
| InChi | InChI=1S/C21H27NO.ClH/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23;/h3-10,19,23H,2,11-16H2,1H3;1H |
| InChiKey | XWLCIDLCEZAOEY-UHFFFAOYSA-N |
| CID | 11957671 |
| Short Description | D2 agonist |
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