INK 128 - MLN0128 | Sapanisertib

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2142

CAS [1224844-38-5]

MF C15H15N7O
MW 309.33

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

INK 128

Description

Potent and selective mTOR inhibitor.

KEYWORDS: INK 128 | supplier | mTOR inhibitor | MLN0128 | Sapanisertib | INK128 | INK-128 | MLN- 0128 | MLN 0128 | CAS [1224844-38-5] | Phosphatidylinositol | mTOR | Inhibitor

AC Hsieh, Y Liu et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature 2012, 485, 55–61.

K Jessen et al. Abstract B148: INK128 is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. Mol. Cancer Ther. 2009, 8(12), S1.

MR Janes et al. Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia. Leukemia. 2013, 27(3), 586-594.

Potent and selective mTOR inhibitor

Chemical name

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine

Parent CAS No.

[1224844-38-5]

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Size	Unit Price	Stock
5 mg	€110.00	In Stock
25 mg	€365.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	€160.00	In Stock
2 x 25 mg	€560.00	In Stock

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INK 128 - MLN0128 | Sapanisertib

Description

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Parent CAS No.

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INK 128 - MLN0128 | Sapanisertib

Description

Chemical name

Parent CAS No.

Related Products

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