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Axon 1390
CAS [702675-74-9]
MF C23H26IN7O2SMW 591.47
BX 795 was initially developed as a PDPK1 inhibitor. Recent study highlighted on its bioactivitiy as a potent and relatively specific inhibitor of TBK1 and closely related IKKε, with IC50 values to be 6, 41, and 111 nM for TBK1, IKKε and PDPK1 respectively.
The hydrochloride salt of BX 795 is available as Axon 3350.
KEYWORDS: BX 795 | supplier | PDK1/TBK1 inhibitor | BX795 | BX-795 | CAS [702675-74-9] | Phosphatidylinositol | IKK | PDPK | PDK1 | TBK | TBK1 | IKK-epsilon
List of publications using BX 795 (Axon 1390) purchased from Axon Medchem
Pyrrolidine-1-carboxylic acid [3-(5-iodo-4-{3-[(thiophene-2-carbonyl)-amino]-propylamino}-pyrimidin-2-ylamino)-phenyl]-amide
[702675-74-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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