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EVP 4593
- Soluble in DMSO
- MF: C22H20N4O
- MW: 356.42
Description
More Information
| Parent CAS No. | 545380-34-5 |
|---|---|
| Chemical Name | N4-(4-phenoxyphenethyl)quinazoline-4,6-diamine |
| SMILES | N1=C2C(C=C(N)C=C2)=C(NCCC2=CC=C(OC3=CC=CC=C3)C=C2)N=C1 |
| MFCD | MFCD06411436 |
| InChi | InChI=1S/C22H20N4O/c23-17-8-11-21-20(14-17)22(26-15-25-21)24-13-12-16-6-9-19(10-7-16)27-18-4-2-1-3-5-18/h1-11,14-15H,12-13,23H2,(H,24,25,26) |
| InChiKey | IBAKVEUZKHOWNG-UHFFFAOYSA-N |
| CID | 509554 |
| Short Description | NF-κB inhibitor |
References
- J Wu et al. Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment. Chem. Biol. 2011, 18(6), 777-793.
- M Tobe et al. A novel structural class of potent inhibitors of NF-kappa B activation: structure-activity relationships and biological effects of 6-aminoquinazoline derivatives. Bioorg. Med. Chem. 2003, 11, 3869–3878.
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