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DCZ0805
Axon 3518
CAS:
2361147-16-0
- Optical Purity: Mixture of diastereomers
- Soluble in DMSO and EtOH
- MF: C33H33N2O9P
- MW: 632.6
Description
DCZ0805 is a suppressor of the NF-κB signaling pathway activation. DCZ0805 treatment arrested the cell at the G0/G1 phase and suppressed multiple myeloma cells survival by inducing apoptosis via extrinsic and intrinsic pathways.
More Information
| Parent CAS No. | 2361147-16-0 |
|---|---|
| Chemical Name | (2S)-Methyl 2-((4-(3,5-dimethoxystyryl)phenoxy)(4-(2-hydroxybenzamido)phenoxy)phosphorylamino)propanoate |
| SMILES | C1C=C(C(=O)NC2C=CC(OP(N[C@@H](C)C(OC)=O)(OC3C=CC(/C=C/C4C=C(OC)C=C(OC)C=4)=CC=3)=O)=CC=2)C(O)=CC=1 |&1:13,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C33H33N2O9P/c1-22(33(38)42-4)35-45(39,44-27-17-13-25(14-18-27)34-32(37)30-7-5-6-8-31(30)36)43-26-15-11-23(12-16-26)9-10-24-19-28(40-2)21-29(20-24)41-3/h5-22,36H,1-4H3,(H,34,37)(H,35,39)/b10-9+/t22-,45?/m0/s1 |
| InChiKey | RTHUMPBVJFTAST-ZPFBOIQBSA-N |
| CID | 165436116 |
| Short Description | NF-κB inhibitor |
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