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IMD-0560
- Soluble in 0.1N NaOH(aq), DMSO and EtOH
- MF: C15H8BrF6NO2
- MW: 428.12
Description
IMD-0560 is a selective IKKβ inhibitor which blocks IκBα phosphorylation and prevents NF-κB p65 nuclear translocation.
More Information
| Parent CAS No. | 439144-66-8 |
|---|---|
| Chemical Name | N-(2,5-Bis(trifluoromethyl)phenyl)-5-bromo-2-hydroxybenzamide |
| SMILES | C1C(O)=C(C(=O)NC2C=C(C(F)(F)F)C=CC=2C(F)(F)F)C=C(Br)C=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C15H8BrF6NO2/c16-8-2-4-12(24)9(6-8)13(25)23-11-5-7(14(17,18)19)1-3-10(11)15(20,21)22/h1-6,24H,(H,23,25) |
| InChiKey | SVGRIJCSKWXOPA-UHFFFAOYSA-N |
| CID | 11464503 |
| Short Description | IKK-2 inhibitor |
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