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PS210
- Soluble in 0.1N NaOH(aq), DMSO and EtOH
- MF: C19H15F3O5
- MW: 380.31
Description
PS210 is a potent and selective activator of PDK1 (AC50 value of 2 μM) that binds to the PIF-pocket and allosterically modulates the active site of PDK1.
More Information
| Parent CAS No. | 1221962-86-2 |
|---|---|
| Chemical Name | 2-(3-Oxo-1-phenyl-3-(4-(trifluoromethyl)phenyl)propyl)malonic acid |
| SMILES | C1C=C(C(=O)CC(C(C(O)=O)C(O)=O)C2C=CC=CC=2)C=CC=1C(F)(F)F |
| MFCD | MFCD32701991 |
| InChi | InChI=1S/C19H15F3O5/c20-19(21,22)13-8-6-12(7-9-13)15(23)10-14(11-4-2-1-3-5-11)16(17(24)25)18(26)27/h1-9,14,16H,10H2,(H,24,25)(H,26,27) |
| InChiKey | MLJPLHGJBUWCBA-UHFFFAOYSA-N |
| CID | 66760004 |
| Short Description | PDK1 activator |
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